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| author | Arun Isaac | 2025-09-08 11:33:43 +0100 |
|---|---|---|
| committer | Arun Isaac | 2025-09-08 11:34:00 +0100 |
| commit | a662340e3005500cf3d76a937ee13e103ff71fb3 (patch) | |
| tree | fe4926e7719dc6c2d313317525de5a36c80f92e7 | |
| parent | 653b5850a4d7833e935889d545e2c0680a5e65d8 (diff) | |
| download | pyhegp-a662340e3005500cf3d76a937ee13e103ff71fb3.tar.gz pyhegp-a662340e3005500cf3d76a937ee13e103ff71fb3.tar.lz pyhegp-a662340e3005500cf3d76a937ee13e103ff71fb3.zip | |
Detail SNP dropping.
| -rw-r--r-- | README.md | 4 |
1 files changed, 2 insertions, 2 deletions
diff --git a/README.md b/README.md index 399b39a..de93fd2 100644 --- a/README.md +++ b/README.md @@ -77,11 +77,11 @@ Data owners generate summary statistics for their data. ``` pyhegp summary genotype.tsv -o summary ``` -They share this with the data broker who pools it to compute the summary statistics of the complete dataset. +They share this with the data broker who pools it to compute the summary statistics of the complete dataset. Any SNPs not common to all summaries will be dropped. ``` pyhegp pool -o complete-summary summary1 summary2 ... ``` -The data broker shares these summary statistics with the data owners. The data owners standardize their data using these summary statistics, and encrypt their genotype and phenotype data using a random key. +The data broker shares these summary statistics with the data owners. The data owners standardize their data using these summary statistics, and encrypt their genotype and phenotype data using a random key. Any SNPs not in `complete-summary` or have a zero standard deviation are dropped. SNPs with a zero standard deviation have no discriminatory power in the analysis. ``` pyhegp encrypt -s complete-summary genotype.tsv phenotype.tsv ``` |